Biography
Dr. Lai is also a clinical investigator with a robust research program dedicated to improving the lives of patients living with chronic liver disease and to help more of them survive to transplant and thrive after. Her research program has been continuously supported by numerous organizations including the National Institutes of Health, American Association for the Study of Liver Diseases (AASLD), American Gastroenterological Association (AGA), American College of Gastroenterology (ACG), American Society of Transplantation (AST), and American Federation for Aging Research (AFAR), in addition to the generous support of grateful patients. She serves as director of the UCSF Health Advancing Research in Clinical Hepatology (ARCH), the research arm of the UCSF Division of GI/Hepatology, as well as director of Patient-Facing Research Core of the NIH-funded UCSF Liver Center.
Dr. Lai earned her B.S. from Stanford University and combined MD/MBA degrees from Tufts University School of Medicine, then completed her clinical training in Internal Medicine at Columbia University, and gastroenterology and advanced/transplant hepatology fellowships at UCSF. Dr. Lai has received many honors for her work including the SF Business Times Top 40 under 40 Leader award, AGA Young Investigator Award in Clinical Science, AST Clinical Science Career Development Award, Young Investigator Award from the International Liver Transplantation Society, and the UCSF Department of Medicine Resident Research Award. Currently, Dr. Lai serves as an Associate Editor for the Hepatology Journal (the premier hepatology journal) and a standing member of the U.S. FDA Gastrointestinal Drug Advisory Committee.
If you are interested in contributing to Dr. Lai's research program, please consider making a tax-deductible contribution: https://makeagift.ucsf.edu/LaiResearchFund
Education
Institution | Degree | Dept or School | End Date |
---|---|---|---|
Osher Collaborative for Integrative Health | Integrative Health | 06/2024 | |
Columbia University Medical Center | Internship/Residency | Internal Medicine | |
Stanford University | B.S. | ||
Tufts University School of Medicine | M.D./M.B.A. | Medicine / Healthcare administration | |
UCSF | Advanced Training in Clinical Research | ||
UCSF | Fellowship in Advanced/Transplant Hepatology | ||
UCSF | Fellowship in Gastroenterology |
Board Certifications
American Board of Internal Medicine
American Board of Internal Medicine - Gastroenterology
Awards & Honors
Award | Conferred By | Date |
---|---|---|
Distinction in Mentoring (UCSF Academic Senate) | UCSF | 2023 |
Long-Term Mentor Award | UCSF Medical School | 2021 |
Young Investigator Award in Clinical Science | American Gastroenterological Association (AGA) | 2020 |
Floyd Rector Internal Medicine Research Mentoring Award | UCSF | 2019 |
Fellow | American Society of Transplantation | 2017 |
AST/Novartis Faculty Development Award (grant) | American Society of Transplantation | 2016 |
Clinical Science Career Development Award | American Society of Transplantation | 2016 |
New Investigator Award | American Geriatrics Society | 2015 |
Young Investigator Award | International Liver Transplantation Society | 2015 |
Top 40 under 40 | San Francisco Business Times | 2015 |
Paul B. Beeson Scholar in Aging Research (grant) | American Federation for Aging Research | 2014 |
Associate Scholar Genius Award (grant) | UCSF Pepper Center | 2014 |
T. Franklin Williams Scholar (grant) | Association of Specialty Professors | 2013 |
Junior Faculty Career Development Award (grant) | American College of Gastroenterology | 2012 |
Transplant Hepatology Fellowship (grant) | American Association for the Study of Liver Diseases | 2011 |
Clinical Research Award (grant) | American College of Gastrenterology | 2011 |
Vanguard Award | International Liver Transplantation Society | 2011 |
Sylvia Allison Kaplan Clinical Research Award | Northern California Kaiser Permanente | 2009 |
Alpha Omega Alpha | Tufts University School of Medicine | 2005 |
Collaboration Interests
I am interested in:
- physician scientist
Clinical Expertise
Alcoholic Liver Disease
Autoimmune Hepatitis
Cirrhosis
Drug-Induced Hepatitis
Fulminant Hepatic Failure
Hemochromatosis
Hepatitis B
Hepatitis C
Hepatocellular Carcinoma (Liver Cancer)
Liver Transplantation
Living Donor Liver Transplantation
Nonalcoholic Fatty Liver Disease
Polycystic Liver Disease
Primary Biliary Cirrhosis
Primary Sclerosing Cholangitis
Program Affiliations
UCSF Liver Center
In the News
Grants and Funding
- The spectrum of cognitive impairment including Alzheimer’s Disease and related dementias after liver transplantation | NIH/NIA | 2023-09-15 - 2028-08-31 | Role: PI
- Investigating the role of frailty on outcomes in acutely ill patients with cirrhosis undergoing liver transplantation in the acute care setting | NIH/NIDDK | 2023-07-15 - 2028-06-30 | Role: PI
- The Impact of Frailty on Liver Transplant Outcomes in Older Adults with Hepatocellular Carcinoma | NIH/NIA | 2023-01-15 - 2027-12-31 | Role: PI
- Predicting post-transplant mortality and global functional health based on pre-transplant functional status in liver transplantation | NIH | 2018-06-15 - 2023-05-31 | Role: PI
- UCSF Liver Center | NIH | 1985-07-01 - 2023-05-31 | Role: Co-Investigator
- Development of a laboratory frailty index to improve prediction of mortality in patients with cirrhosis awaiting liver transplantation | NIH | 2020-05-01 - 2022-04-30 | Role: Principal Investigator
- Frailty and Functional Status in Older Liver Transplant Patients | NIH | 2014-09-15 - 2019-08-31 | Role: Principal Investigator
- Global Functional Status in the Older Liver Transplant Candidate | NIH | 2013-08-15 - 2015-07-31 | Role: Principal Investigator
Research Narrative
Dr. Lai has engaged in research investigating clinical outcomes in patients with chronic liver disease. Her research focuses on three main areas:
1) Understanding the impact of functional status and physiologic reserve (i.e., frailty) in patients with cirrhosis awaiting liver transplantation (actively enrolling)
2) Evaluating the association between chronic hepatitis C and systemic inflammation with Vitamin D status and bone mineral density (actively enrolling)
3) Characterizing patterns of liver allocation and distribution and their association with liver transplant outcomes (both pre- and post-transplant) on a national level
Research Interests
Impact of function status in patients on the liver-transplant waiting list
Hepatitis C virus (HCV)
Patterns of donor liver allocation and liver transplant outcomes
Publications
- Transforming liver transplant allocation with artificial intelligence and machine learning: a systematic review.Pruinelli L, Balakrishnan K, Ma S, Li Z, Wall A, Lai JC, Schold JD, Pruett T, Simon G| | PubMed
- Cannabis and liver transplant in the era of legalization: Effects of pretransplant cannabis use on postoperative opioid use and transplant outcomes.Runge A, Loeb B, Shui AM, Fenton C, Lai J, Rubin J| | PubMed
- Coproducing a health advocate intervention for pediatric liver transplant recipients using a human-centered design.Cheung T, Squires JE, Bautista B, Milionis C, Prugh J, Hsu E, Ebel NH, Campbell K, Vittorio J, Bucuvalas JC, Gottlieb LM, Lyles CR, Lai JC, Wadhwani SI| | PubMed
- Erratum: Pain in chronic liver disease compared to other chronic conditions: Results from a nationally representative cohort study.Zhang GY, Cortella A, Lai JC, Rubin JB| | PubMed
- Acute-on-chronic liver failure (ACLF): the 'Kyoto Consensus'-steps from Asia.Choudhury A, Kulkarni AV, Arora V, Soin AS, Dokmeci AK, Chowdhury A, Koshy A, Duseja A, Kumar A, Mishra AK, Patwa AK, Sood A, Roy A, Shukla A, Chan A, Krag A, Mukund A, Mandot A, Goel A, Butt AS, Sahney A, Shrestha A, Cárdenas A, Di Giorgio A, Arora A, Anand AC, Dhawan A, Jindal A, Saraya A, Srivastava A, Kumar A, Kaewdech A, Pande A, Rastogi A, Valsan A, Goel A, Kumar A, Singal AK, Tanaka A, Coilly A, Singh A, Meena BL, Jagadisan B, Sharma BC, Lal BB, Eapen CE, Yaghi C, Kedarisetty CK, Kim CW, Panackel C, Yu C, Kalal CR, Bihari C, Huang CH, Vasishtha C, Jansen C, Strassburg C, Lin CY, Karvellas CJ, Lesmana CRA, Philips CA, Shawcross D, Kapoor D, Agrawal D, Payawal DA, Praharaj DL, Jothimani D, Song DS, Kim DJ, Kim DS, Zhongping D, Karim F, Durand F, Shiha GE, D'Amico G, Lau GK, Pati GK, Narro GEC, Lee GH, Adali G, Dhakal GP, Szabo G, Lin HC, Li H, Nair HK, Devarbhavi H, Tevethia H, Ghazinian H, Ilango H, Yu HL, Hasan I, Fernandez J, George J, Behari J, Fung J, Bajaj J, Benjamin J, Lai JC, Jia J, Hu JH, Chen JJ, Hou JL, Yang JM, Chang J, Trebicka J, Kalf JC, Sollano JD, Varghese J, Arab JP, Li J, Reddy KR, Raja K, Panda K, Kajal K, Kumar K, Madan K, Kalista KF, Thanapirom K, Win KM, Suk KT, Devadas K, Lesmana LA, Kamani L, Premkumar M, Niriella MA, Al Mahtab M, Yuen MF, Sayed MH, Alla M, Wadhawan M, Sharma MK, Sahu M, Prasad M, Muthiah MD, Schulz M, Bajpai M, Reddy MS, Praktiknjo M, Yu ML, Prasad M, Sharma M, Elbasiony M, Eslam M, Azam MG, Rela M, Desai MS, Vij M, Mahmud N, Choudhary NS, Marannan NK, Ormeci N, Saraf N, Verma N, Nakayama N, Kawada N, Goyal O, Yokosuka O, Rao PN, Angeli P, Parikh P, Kamath PS, Thuluvath PJ, Lingohr P, Ranjan P, Bhangui P, Rathi P, Sakhuja P, Puri P, Ning Q, Dhiman RK, Kumar R, Vijayaraghavan R, Khanna R, Maiwall R, Mohanka R, Moreau R, Gani RA, Loomba R, Mehtani R, Rajaram RB, Hamid SS, Palnitkar S, Lal S, Biswas S, Chirapongsathorn S, Agarwal S, Sachdeva S, Saigal S, Kumar SE, Violeta S, Singh SP, Mochida S, Mukewar S, Alam S, Lim SG, Alam S, Venishetty S, Sundaram SS, Shetty S, Bhatia S, Singh SA, Kottilil S, Strasser S, Shasthry SM, Maung ST, Tan SS, Treeprasertsuk S, Asthana S, Manekeller S, Gupta S, Acharya SK, K C S, Maharshi S, Asrani S, Dadhich S, Taneja S, Giri S, Singh S, Chen T, Gupta T, Kanda T, Tanwandee T, Piratvishuth T, Spengler U, Prasad VGM, Midha V, Rakhmetova V, Arroyo V, Sood V, Br VK, Wong VW, Pamecha V, Singh V, Dayal VM, Saraswat VA, Kim W, Jafri W, Gu W, Jun WY, Qi X, Chawla YK, Kim YJ, Shi Y, Abbas Z, Kumar G, Shiina S, Wei L, Omata M, Sarin SK, APASL-ACLF Research Consortium (AARC) for APASL-ACLF working party| | PubMed
- Sarcopenia As a Predictor of Survival and Complications of Patients With Cirrhosis After Liver Transplantation: A Systematic Review and Meta-Analysis.Markakis GE, Lai JC, Karakousis ND, Papatheodoridis GV, Psaltopoulou T, Merli M, Sergentanis TN, Cholongitas E| | PubMed
- Oral LPCN 1148 improves sarcopenia and hepatic encephalopathy in male patients with cirrhosis: A randomized, placebo-controlled phase 2 trial.Bruno BJ, Weavil JC, Ogle J, Chidambaram N, Carey EJ, Danford CJ, Fricker ZP, Galati JS, Lee WM, Mantry PS, Shetty K, DelConte A, Patel MV, Lai JC, Sanyal AJ| | PubMed
- Differential aging trends among candidates for liver transplant with and without HCC.Jutras G, Mehta N, Lai JC| | PubMed
- The pervasive impact of frailty on ovarian cancer care and the role of prehabilitation: Qualitative perspectives of key stakeholders.Cham S, Pozzar RA, Horowitz N, Feltmate C, Matulonis UA, Lai JC, Wright AA| | PubMed
- Material economic hardships are associated with adverse 1-year outcomes after pediatric liver transplantation: Prospective cohort results from the multicenter SOCIAL-Tx Study.Wadhwani SI, Squires JE, Hsu E, Gupta N, Campbell K, Zielsdorf S, Vittorio J, Desai DM, Ebel NH, Shui AM, Bucuvalas JC, Gottlieb LM, Lyles CR, Lai JC, Society of Pediatric Liver Transplantation| | PubMed
- Transforming liver transplant allocation with artificial intelligence and machine learning: a systematic review.Pruinelli L, Balakrishnan K, Ma S, Li Z, Wall A, Lai JC, Schold JD, Pruett T, Simon G| | PubMed
- Cannabis and liver transplant in the era of legalization: Effects of pretransplant cannabis use on postoperative opioid use and transplant outcomes.Runge A, Loeb B, Shui AM, Fenton C, Lai J, Rubin J| | PubMed
- Coproducing a health advocate intervention for pediatric liver transplant recipients using a human-centered design.Cheung T, Squires JE, Bautista B, Milionis C, Prugh J, Hsu E, Ebel NH, Campbell K, Vittorio J, Bucuvalas JC, Gottlieb LM, Lyles CR, Lai JC, Wadhwani SI| | PubMed
- Erratum: Pain in chronic liver disease compared to other chronic conditions: Results from a nationally representative cohort study.Zhang GY, Cortella A, Lai JC, Rubin JB| | PubMed
- Acute-on-chronic liver failure (ACLF): the 'Kyoto Consensus'-steps from Asia.Choudhury A, Kulkarni AV, Arora V, Soin AS, Dokmeci AK, Chowdhury A, Koshy A, Duseja A, Kumar A, Mishra AK, Patwa AK, Sood A, Roy A, Shukla A, Chan A, Krag A, Mukund A, Mandot A, Goel A, Butt AS, Sahney A, Shrestha A, Cárdenas A, Di Giorgio A, Arora A, Anand AC, Dhawan A, Jindal A, Saraya A, Srivastava A, Kumar A, Kaewdech A, Pande A, Rastogi A, Valsan A, Goel A, Kumar A, Singal AK, Tanaka A, Coilly A, Singh A, Meena BL, Jagadisan B, Sharma BC, Lal BB, Eapen CE, Yaghi C, Kedarisetty CK, Kim CW, Panackel C, Yu C, Kalal CR, Bihari C, Huang CH, Vasishtha C, Jansen C, Strassburg C, Lin CY, Karvellas CJ, Lesmana CRA, Philips CA, Shawcross D, Kapoor D, Agrawal D, Payawal DA, Praharaj DL, Jothimani D, Song DS, Kim DJ, Kim DS, Zhongping D, Karim F, Durand F, Shiha GE, D'Amico G, Lau GK, Pati GK, Narro GEC, Lee GH, Adali G, Dhakal GP, Szabo G, Lin HC, Li H, Nair HK, Devarbhavi H, Tevethia H, Ghazinian H, Ilango H, Yu HL, Hasan I, Fernandez J, George J, Behari J, Fung J, Bajaj J, Benjamin J, Lai JC, Jia J, Hu JH, Chen JJ, Hou JL, Yang JM, Chang J, Trebicka J, Kalf JC, Sollano JD, Varghese J, Arab JP, Li J, Reddy KR, Raja K, Panda K, Kajal K, Kumar K, Madan K, Kalista KF, Thanapirom K, Win KM, Suk KT, Devadas K, Lesmana LA, Kamani L, Premkumar M, Niriella MA, Al Mahtab M, Yuen MF, Sayed MH, Alla M, Wadhawan M, Sharma MK, Sahu M, Prasad M, Muthiah MD, Schulz M, Bajpai M, Reddy MS, Praktiknjo M, Yu ML, Prasad M, Sharma M, Elbasiony M, Eslam M, Azam MG, Rela M, Desai MS, Vij M, Mahmud N, Choudhary NS, Marannan NK, Ormeci N, Saraf N, Verma N, Nakayama N, Kawada N, Goyal O, Yokosuka O, Rao PN, Angeli P, Parikh P, Kamath PS, Thuluvath PJ, Lingohr P, Ranjan P, Bhangui P, Rathi P, Sakhuja P, Puri P, Ning Q, Dhiman RK, Kumar R, Vijayaraghavan R, Khanna R, Maiwall R, Mohanka R, Moreau R, Gani RA, Loomba R, Mehtani R, Rajaram RB, Hamid SS, Palnitkar S, Lal S, Biswas S, Chirapongsathorn S, Agarwal S, Sachdeva S, Saigal S, Kumar SE, Violeta S, Singh SP, Mochida S, Mukewar S, Alam S, Lim SG, Alam S, Venishetty S, Sundaram SS, Shetty S, Bhatia S, Singh SA, Kottilil S, Strasser S, Shasthry SM, Maung ST, Tan SS, Treeprasertsuk S, Asthana S, Manekeller S, Gupta S, Acharya SK, K C S, Maharshi S, Asrani S, Dadhich S, Taneja S, Giri S, Singh S, Chen T, Gupta T, Kanda T, Tanwandee T, Piratvishuth T, Spengler U, Prasad VGM, Midha V, Rakhmetova V, Arroyo V, Sood V, Br VK, Wong VW, Pamecha V, Singh V, Dayal VM, Saraswat VA, Kim W, Jafri W, Gu W, Jun WY, Qi X, Chawla YK, Kim YJ, Shi Y, Abbas Z, Kumar G, Shiina S, Wei L, Omata M, Sarin SK, APASL-ACLF Research Consortium (AARC) for APASL-ACLF working party| | PubMed
- Sarcopenia As a Predictor of Survival and Complications of Patients With Cirrhosis After Liver Transplantation: A Systematic Review and Meta-Analysis.Markakis GE, Lai JC, Karakousis ND, Papatheodoridis GV, Psaltopoulou T, Merli M, Sergentanis TN, Cholongitas E| | PubMed
- Oral LPCN 1148 improves sarcopenia and hepatic encephalopathy in male patients with cirrhosis: A randomized, placebo-controlled phase 2 trial.Bruno BJ, Weavil JC, Ogle J, Chidambaram N, Carey EJ, Danford CJ, Fricker ZP, Galati JS, Lee WM, Mantry PS, Shetty K, DelConte A, Patel MV, Lai JC, Sanyal AJ| | PubMed
- Differential aging trends among candidates for liver transplant with and without HCC.Jutras G, Mehta N, Lai JC| | PubMed
- The pervasive impact of frailty on ovarian cancer care and the role of prehabilitation: Qualitative perspectives of key stakeholders.Cham S, Pozzar RA, Horowitz N, Feltmate C, Matulonis UA, Lai JC, Wright AA| | PubMed
- Material economic hardships are associated with adverse 1-year outcomes after pediatric liver transplantation: Prospective cohort results from the multicenter SOCIAL-Tx Study.Wadhwani SI, Squires JE, Hsu E, Gupta N, Campbell K, Zielsdorf S, Vittorio J, Desai DM, Ebel NH, Shui AM, Bucuvalas JC, Gottlieb LM, Lyles CR, Lai JC, Society of Pediatric Liver Transplantation| | PubMed
- Pain in chronic liver disease compared to other chronic conditions: Results from a contemporary nationally representative cohort study.Zhang GY, Cortella A, Lai JC, Rubin JB| | PubMed
- Sex Differences in Patient-Reported Outcomes and Perception of Ascites Burden Among Outpatients With Decompensated Cirrhosis and Ascites.Wong F, Reddy KR, Tandon P, Lai JC, Garcia-Tsao G, O'Leary JG, Biggins SW, Vargas HE, Thacker L, Kamath PS, Bajaj JS, NACSELD III Study Group| | PubMed
- Prognostic Communication, Symptom Burden, Psychological Distress, and Quality of Life Among Patients With Decompensated Cirrhosis.Donlan J, Kaplan A, Noll A, Pintro K, Horick N, Zeng C, Edelen M, Soetan Z, Comrie C, Indriolo T, Li L, Zhu E, Armstrong ME, Thompson LL, Zhou J, Diop MS, Mason N, Engel KG, Rowland M, Kenimer S, O'Brien K, Lai JC, Jackson V, Chung RT, El-Jawahri A, Ufere NN| | PubMed
- Clinical Sentiment Analysis by Large Language Models Enhances the Prediction of Hepatorenal Syndrome in Decompensated Cirrhosis.Lai M, Fenton C, Rubin J, Huang CY, Pletcher M, Lai JC, Cullaro G, Ge J| | PubMed
- Portal Hypertensive Gastropathy and MELD-Na Score Predict Recurrent Gastrointestinal Bleeding After TIPSS: An ALTA Group Study.Hu K, Sedki M, Kwong A, Kesselman A, Kolli KP, Morelli G, Spengler E, Said A, Lai J, Desai A, Paul S, Frenette C, Fallon M, German M, Verna E, Boike J, Gregory D, Thornburg B, VanWagner L, Goel A, Advancing Liver Therapeutic Approaches (ALTA) Study Group| | PubMed
- Novel autoantibody targets identified in patients with autoimmune hepatitis (AIH) by PhIP-Seq reveals pathogenic insights.Klepper A, Asaki J, Kung AF, Vazquez SE, Bodansky A, Mitchell A, Mann SA, Zorn K, Avila-Vargas I, Kari S, Tekeste M, Castro J, Lee B, Duarte M, Khalili M, Yang M, Wolters P, Price J, Perito E, Feng S, Maher JJ, Lai JC, Weiler-Normann C, Lohse AW, DeRisi J, Tana M| | PubMed
- Psychological Distress Is Prevalent and Interdependent Among Patients With Decompensated Cirrhosis and Their Caregivers.Ufere NN, Zeng C, Donlan J, Shalev D, Kaplan A, Noll A, Liu A, Pintro K, Horick N, Indriolo T, Li L, Zhu E, Armstrong ME, Mason N, Engel KG, Rowland M, O'Brien K, Kenimer S, Diop MS, Jackson V, Lai JC, Chung RT, Jacobs JM, Edelen MO, El-Jawahri A| | PubMed
- A patient-centered approach to dietary supplements for patients with chronic liver disease.Lai JC, Ring M, Dhruva A, Yeh GY| | PubMed
- Evaluating the positive predictive value of code-based identification of cirrhosis and its complications utilizing GPT-4.Far AT, Bastani A, Lee A, Gologorskaya O, Huang CY, Pletcher MJ, Lai JC, Ge J| | PubMed
- Predictors of long-term clinical outcomes after TIPS: An ALTA group study.Nobel YR, Boike JR, Mazumder NR, Thornburg B, Hoffman R, Kolli KP, Fallon M, Lai JC, Morelli G, Spengler EK, Said A, Desai AP, Paul S, Goel A, Hu K, Frenette C, Gregory D, Padilla C, Zhang Y, VanWagner LB, Verna EC, Advancing Liver Therapeutic Approaches (ALTA) Study Group| | PubMed
- Investigating the Association between Steatotic Liver Disease and CKD in a Nationally Representative Sample.Lai M, Lai JC, Allegretti AS, Patidar KR, Cullaro G| | PubMed
- Challenges in Liver Transplantation for Hepatocellular Carcinoma: A Review of Current Controversies.Mauro E, Sanduzzi-Zamparelli M, Jutras G, Garcia R, Soler Perromat A, Llarch N, Holguin Arce V, Ruiz P, Rimola J, Lopez E, Ferrer-Fàbrega J, García-Criado Á, Colmenero J, Lai JC, Forner A| | PubMed
- Decreasing Case Fatality Rates for Patients With Cirrhosis Infected With SARS-CoV-2: A National COVID Cohort Collaborative Study.Ge J, Far AT, Digitale JC, Pletcher MJ, Lai JC, National COVID Cohort Collaborative (N3C) Consortium| | PubMed
- Cystatin C and the difference between cystatin C and serum creatinine: Improved metrics to predict waitlist mortality among patients with decompensated cirrhosis.Cullaro G, Allegretti AS, Patidar KR, Verna EC, Lai JC| | PubMed
- Liver transplantation provides survival benefit at all levels of frailty: From the Multicenter Functional Assessment in Liver Transplantation Study.Wang M, Chiou SH, Ganger D, Ruck J, Huang CY, Kappus MR, King EA, Ladner DP, Rahimi RS, Duarte-Rojo A, Volk ML, Tevar AD, Verna EC, Lai JC| | PubMed
- The Liver Frailty Index enhances mortality risk prediction above and beyond MELD 3.0 alone.Wang M, Shui AM, Huang CY, Kappus MR, Rahimi R, Verna EC, Ruck J, King EA, Ladner DP, Tevar AD, Volk ML, Duarte-Rojo A, Ganger D, Lai JC| | PubMed
- From prognostication to therapeutics: Four key questions to accelerate the development of therapeutics for patients with acute-on-chronic liver failure.Lai JC, Sarin SK, Gines P| | PubMed
- The Complex Relationship Between Pain, Mental Health, and Quality-of-Life in Patients With Cirrhosis Undergoing Liver Transplant Evaluation.Wong RJ, Loeb R, Seal KH, Barry F, Stark Kent D, Seetharaman S, Sharma A, Lai JC, Rubin JB| | PubMed
- Association between protein-energy malnutrition and healthcare use among adult patients after liver transplantation: A retrospective cohort study.Wang M, Shui AM, Rubin JB, Pyrsopoulos N, Lai JC| | PubMed
- Reply: Refining retrieval and chunking strategies for enhanced clinical reliability of large language models in liver disease.Ge J, Sun S, Owens J, Galvez V, Gologorskaya O, Lai JC, Pletcher MJ, Lai K| | PubMed
- Associations between hospital-level socioeconomic patient mix and rates of central line-associated bloodstream infections in short bowel syndrome: A retrospective cohort study.Gutierrez SA, Chiou SH, Raghu V, Cole CR, Rhee S, Lai JC, Wadhwani SI| | PubMed
- Clinically relevant cut-points for changes in the Liver Frailty Index are associated with waitlist mortality in patients with cirrhosis.Wang M, Shui AM, Ruck J, Huang CY, Verna EC, King EA, Ladner DP, Ganger D, Kappus M, Rahimi R, Tevar AD, Duarte-Rojo A, Lai JC| | PubMed
- Caregiver-reported symptom burden and preferences for therapeutic goals in pediatric primary sclerosing cholangitis.Shifman HP, Hatchett J, Pai RA, Safer R, Gomel R, Vyas M, Li M, Lai JC, Wadhwani SI| | PubMed
- The Liver Frailty Index: a model for establishing organ-specific frailty metrics across all solid organ transplantation.Jutras G, Lai JC| | PubMed
- The burden of significant pain in the cirrhosis population: Risk factors, analgesic use, and impact on health care utilization and clinical outcomes.Rubin JB, Loeb R, Fenton C, Huang CY, Keyhani S, Seal KH, Lai JC| | PubMed
- Patient-focused drug development in primary sclerosing cholangitis: Insights on patient priorities and involvement in clinical trials.Li M, Pai RA, Gomel R, Vyas M, Callif SC, Hatchett J, Bowlus CL, Lai JC| | PubMed
- Applying Metabolomics and Aptamer-based Proteomics to Determine Pathophysiologic Differences in Decompensated Cirrhosis Patients Hospitalized with Acute Kidney Injury.Cullaro G, Allegretti AS, Patidar KR, Verna EC, Lai JC| | PubMed
- The influence of neighborhood income on healthcare utilization in pediatric liver transplant.Gutierrez SA, Chiou SH, Rhee S, Lai JC, Wadhwani SI| | PubMed
- Frailty, Sarcopenia, and Nutrition in Patients With Cirrhosis.Lai JC| | PubMed
- Nutritional aspects of prehabilitation in adults with cirrhosis awaiting liver transplant.Cruz C, Prado CM, Gillis C, Martindale R, Bémeur C, Lai JC, Tandon P| | PubMed
- Outpatient mean arterial pressure: A potentially modifiable risk for acute kidney injury and death among patients with cirrhosis.Cullaro G, Chiou SH, Fenton C, Ge J, McCulloch CE, Rubin J, Shui AM, Yao F, Lai JC| | PubMed
- Quality measures in pre-liver transplant care by the Practice Metrics Committee of the American Association for the Study of Liver Diseases.Brahmania M, Kuo A, Tapper EB, Volk ML, Vittorio JM, Ghabril M, Morgan TR, Kanwal F, Parikh ND, Martin P, Mehta S, Winder GS, Im GY, Goldberg D, Lai JC, Duarte-Rojo A, Paredes AH, Patel AA, Sahota A, McElroy LM, Thomas C, Wall AE, Malinis M, Aslam S, Simonetto DA, Ufere NN, Ramakrishnan S, Flynn MM, Ibrahim Y, Asrani SK, Serper M| | PubMed
- The association between mean arterial pressure and acute kidney injury reversal among patients with decompensated cirrhosis.Cullaro G, Allegretti AS, Fenton C, Ge J, Patidar KR, Rubin J, Sharma A, Lai JC| | PubMed
- Caregiver Perceptions of Social Risk Screening in Pediatric Liver Transplantation: From the Multicenter SOCIAL-Tx Study.Wadhwani SI, Kruse G, Squires J, Ebel N, Gupta N, Campbell K, Hsu E, Zielsdorf S, Vittorio J, Desai DM, Bucuvalas JC, Gottlieb LM, Lai JC| | PubMed
- Prompt Engineering for Generative Artificial Intelligence in Gastroenterology and Hepatology.Ge J, Chen IY, Pletcher MJ, Lai JC| | PubMed
- Development of a liver disease-specific large language model chat interface using retrieval-augmented generation.Ge J, Sun S, Owens J, Galvez V, Gologorskaya O, Lai JC, Pletcher MJ, Lai K| | PubMed
- Applying human-centered design to the construction of a cirrhosis management clinical decision support system.Ge J, Buenaventura A, Berrean B, Purvis J, Fontil V, Lai JC, Pletcher MJ| | PubMed
- Outcomes of High-Grade Immune Checkpoint Inhibitor Hepatitis in Hospitalized and Nonhospitalized Patients.Li M, Wong D, Sack JS, Vogel AS, Hodi FS, Fong L, Lai JC, Zucker SD, Grover S| | PubMed
- A modified Hospital Frailty Risk Score for patients with cirrhosis undergoing abdominal operations.Calthorpe L, Chiou SH, Rubin J, Huang CY, Feng S, Lai J| | PubMed
- Financial burden following adult liver transplantation is common and associated with adverse recipient outcomes.Ufere NN, Serper M, Kaplan A, Horick N, Indriolo T, Li L, Satapathy N, Donlan J, Castano Jimenez JC, Lago-Hernandez C, Lieber S, Gonzalez C, Keegan E, Schoener K, Bethea E, Dageforde LA, Yeh H, El-Jawahri A, Park ER, Vodkin I, Schonfeld E, Nipp R, Desai A, Lai JC| | PubMed
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- Systematic Review and Meta-Analysis of Brief Cognitive Instruments to Evaluate Suspected Dementia in Chinese-Speaking Populations.Yu RC, Lai JC, Hui EK, Mukadam N, Kapur N, Stott J, Livingston G| | PubMed
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- Time to embrace PROMIS-29 as the standard health-related quality of life instrument for patients with cirrhosis.Tapper EB, Lai JC| | PubMed
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- Actionable Solutions to Achieve Health Equity in Chronic Liver Disease.Jones PD, Lai JC, Bajaj JS, Kanwal F| | PubMed
- The tele-liver frailty index (TeLeFI): development of a novel frailty tool in patients with cirrhosis via telemedicine.Wang M, Shui AM, Barry F, Verna E, Kent D, Yao F, Seetharaman S, Berry K, Grubbs RK, George G, Huang CY, Duarte-Rojo A, Lai JC| | PubMed
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- Promoting Prognostic Understanding and Health Equity for Patients With Advanced Liver Disease: Using "Best Case/Worst Case".Ufere NN, El-Jawahri A, Ritchie C, Lai JC, Schwarze ML| | PubMed
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- The impact of right atrial pressure on outcomes in patients undergoing TIPS, an ALTA group study.Bommena S, Mahmud N, Boike JR, Thornburg BG, Kolli KP, Lai JC, German M, Morelli G, Spengler E, Said A, Desai AP, Junna S, Paul S, Frenette C, Verna EC, Goel A, Gregory D, Padilla C, VanWagner LB, Fallon MB, Advancing Liver Therapeutic Approaches (ALTA) Study Group| | PubMed
- Introducing Norah Terrault, MD, MPH, Our 2023 AASLD President.Peters MG, Lai JC| | PubMed
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- "Beyond MELD" - Emerging strategies and technologies for improving mortality prediction, organ allocation and outcomes in liver transplantation.Ge J, Kim WR, Lai JC, Kwong AJ| | PubMed
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- Racial/ethnic disparities in wait-list outcomes are only partly explained by socioeconomic deprivation among children awaiting liver transplantation.Wadhwani SI, Ge J, Gottlieb L, Lyles C, Beck AF, Bucuvalas J, Neuhaus J, Kotagal U, Lai JC| | PubMed
- Frailty is associated with increased risk of cirrhosis disease progression and death.Wang S, Whitlock R, Xu C, Taneja S, Singh S, Abraldes JG, Burak KW, Bailey RJ, Lai JC, Tandon P| | PubMed
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- An Analysis of Free-Text Refusals as an Indicator of Readiness to Accept Organ Offers in Liver Transplantation.Ge J, Ku E, Roll GR, Lai JC| | PubMed
- The Prediction of In-Hospital Mortality in Decompensated Cirrhosis with Acute-on-Chronic Liver Failure.Wong F, Reddy KR, Tandon P, Lai JC, Jagarlamudi N, Weir V, Kok B, Kalainy S, Srisengfa YT, Albhaisi S, Reuter B, Acharya C, Shaw J, Thacker LR, Bajaj JS| | PubMed
- Sex-based Disparities in Hepatocellular Carcinoma Recurrence After Liver Transplantation.Cullaro G, Rubin J, Mehta N, Yao F, Verna EC, Lai JC| | PubMed
- Pilot Randomized Controlled Trial of an Advance Care Planning Video Decision Tool for Patients With Advanced Liver Disease.Ufere NN, Robinson B, Donlan J, Indriolo T, Bloom J, Scherrer A, Mason NM, Patel A, Lai JC, Chung RT, Volandes A, El-Jawahri A| | PubMed
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- Frailty and Risk of Serious Infections in Biologic-treated Patients With Inflammatory Bowel Diseases.Singh S, Heien HC, Sangaralingham L, Shah ND, Lai JC, Sandborn WJ, Moore AA| | PubMed
- Addressing Social Adversity to Improve Outcomes for Children After Liver Transplant.Wadhwani SI, Gottlieb L, Bucuvalas JC, Lyles C, Lai JC| | PubMed
- Outcomes After TIPS for Ascites and Variceal Bleeding in a Contemporary Era-An ALTA Group Study.Boike JR, Mazumder NR, Kolli KP, Ge J, German M, Jest N, Morelli G, Spengler E, Said A, Lai JC, Desai AP, Couri T, Paul S, Frenette C, Verna EC, Rahim U, Goel A, Gregory D, Thornburg B, VanWagner LB, Advancing Liver Therapeutic Approaches (ALTA) Study Group| | PubMed
- Thinking Ahead: Advance Care Planning for Patients With Cirrhosis.Deng LX, Tana MM, Lai JC| | PubMed
- Malnutrition, Frailty, and Sarcopenia in Patients With Cirrhosis: 2021 Practice Guidance by the American Association for the Study of Liver Diseases.Lai JC, Tandon P, Bernal W, Tapper EB, Ekong U, Dasarathy S, Carey EJ| | PubMed
- Correcting the sex disparity in access to liver transplantation: Lest perfect be the enemy of better.Kwong AJ, Lai JC, Kim WR| | PubMed
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- Temporal Trends and Evolving Outcomes After Simultaneous Liver-Kidney Transplantation: Results from the US SLKT Consortium.Cullaro G, Sharma P, Jo J, Rassiwala J, VanWagner LB, Wong R, Lai JC, Magee J, Schluger A, Barman P, Patel YA, Walter K, Biggins SW, Verna EC| | PubMed
- Symptom Burden Is Associated with Increased Emergency Department Utilization among Patients with Cirrhosis.Deng LX, Kent DS, O'Riordan DL, Pantilat SZ, Lai JC, Bischoff KE| | PubMed
- Inpatient Frailty Assessment Is Feasible and Predicts Nonhome Discharge and Mortality in Decompensated Cirrhosis.Serper M, Tao SY, Kent DS, Garren P, Burdzy AE, Lai JC, Gougol A, Bloomer PM, Reddy KR, Dunn MA, Duarte-Rojo A| | PubMed
- Association Between Kidney Dysfunction Types and Mortality Among Hospitalized Patients with Cirrhosis.Cullaro G, Rubin JB, Fortune BE, Crawford CV, Verna EC, Hsu CY, Liu KD, Brown RS, Lai JC, Rosenblatt R| | PubMed
- Outcomes of SARS-CoV-2 Infection in Patients With Chronic Liver Disease and Cirrhosis: A National COVID Cohort Collaborative Study.Ge J, Pletcher MJ, Lai JC, N3C Consortium| | PubMed
- The relationship between frailty and cirrhosis etiology: From the Functional Assessment in Liver Transplantation (FrAILT) Study.Xu CQ, Mohamad Y, Kappus MR, Boyarsky B, Ganger DR, Volk ML, Rahimi RS, Duarte-Rojo A, McAdams-DeMarco M, Segev DL, Ladner DP, Verna EC, Grab J, Tincopa M, Dunn MA, Lai JC| | PubMed
- Admission Urinary and Serum Metabolites Predict Renal Outcomes in Hospitalized Patients With Cirrhosis.Bajaj JS, Garcia-Tsao G, Reddy KR, O'Leary JG, Vargas HE, Lai JC, Kamath PS, Tandon P, Subramanian RM, Thuluvath P, Fagan A, Sehrawat T, de la Rosa Rodriguez R, Thacker LR, Wong F| | PubMed
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- Developing Priorities for Palliative Care Research in Advanced Liver Disease: A Multidisciplinary Approach.Patel AA, Woodrell C, Ufere NN, Hansen L, Tandon P, Verma M, Lai J, Pinotti R, Rakoski M, and on behalf of the Palliative Care Education, Advocacy, and Research in Liver Disease (PEARL) Wor| | PubMed
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- A Multicenter Pilot Randomized Clinical Trial of a Home-Based Exercise Program for Patients With Cirrhosis: The Strength Training Intervention (STRIVE).Lai JC, Dodge JL, Kappus MR, Wong R, Mohamad Y, Segev DL, McAdams-DeMarco M| | PubMed
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- Renal Recovery and Mortality Risk among Patients with Hepatorenal Syndrome Receiving Chronic Maintenance Dialysis.McAllister S, Lai JC, Copeland TP, Johansen KL, McCulloch CE, Kwong YD, Seth D, Grimes B, Ku E| | PubMed
- Association of Frailty and Sex With Wait List Mortality in Liver Transplant Candidates in the Multicenter Functional Assessment in Liver Transplantation (FrAILT) Study.Lai JC, Ganger DR, Volk ML, Dodge JL, Dunn MA, Duarte-Rojo A, Kappus MR, Rahimi RS, Ladner DP, Boyarsky B, McAdams-DeMarco M, Segev DL, McCulloch CE, Verna EC| | PubMed
- Assessment of the Frail Patient With End-Stage Liver Disease: A Practical Overview of Sarcopenia, Physical Function, and Disability.Williams FR, Milliken D, Lai JC, Armstrong MJ| | PubMed
- Implementing a Height-Based Rule for the Allocation of Pediatric Donor Livers to Adults: A Liver Simulated Allocation Model Study.Ge J, Wood N, Segev DL, Lai JC, Gentry S| | PubMed
- Low Predictability of Readmissions and Death Using Machine Learning in Cirrhosis.Hu C, Anjur V, Saboo K, Reddy KR, O'Leary J, Tandon P, Wong F, Garcia-Tsao G, Kamath PS, Lai JC, Biggins SW, Fallon MB, Thuluvath P, Subramanian RM, Maliakkal B, Vargas H, Thacker LR, Iyer RK, Bajaj JS| | PubMed
- Evaluating the Associations Between the Liver Frailty Index and Karnofsky Performance Status With Waitlist Mortality.Xu CQ, Yao F, Mohamad Y, Wong R, Kent D, Seetharaman S, Srisengfa Y, Lai JC| | PubMed
- National Early Career Transplant Hepatologist Survey: Compensation, Burnout, and Job Satisfaction.Kriss M, Te HS, Verna EC, VanWagner LB, Scott FI, Lai JC| | PubMed
- Nonalcoholic Fatty Liver Disease and Diabetes Mellitus Are Associated With Post-Transjugular Intrahepatic Portosystemic Shunt Renal Dysfunction: An Advancing Liver Therapeutic Approaches Group Study.Ge J, Lai JC, Boike JR, German M, Jest N, Morelli G, Spengler E, Said A, Lee A, Hristov A, Desai AP, Junna S, Pokhrel B, Couri T, Paul S, Frenette C, Christian-Miller N, Laurito M, Verna EC, Rahim U, Goel A, Das A, Pine S, Gregory D, VanWagner LB, Kolli KP, Advancing Liver Therapeutic Approaches (ALTA) Study Group| | PubMed
- Increased Risk of ACLF and Inpatient Mortality in Hospitalized Patients with Cirrhosis and Hepatic Hydrothorax.O'Leary JG, Rajender Reddy K, Tandon P, Biggins SW, Wong F, Kamath PS, Garcia-Tsao G, Maliakkal B, Lai JC, Fallon M, Vargas HE, Thuluvath P, Subramanian R, Thacker LR, Bajaj JS| | PubMed
- Kefir Peptides Prevent Estrogen Deficiency-Induced Bone Loss and Modulate the Structure of the Gut Microbiota in Ovariectomized Mice.Tu MY, Han KY, Chang GR, Lai GD, Chang KY, Chen CF, Lai JC, Lai CY, Chen HL, Chen CM| | PubMed
- Identifying an Optimal Liver Frailty Index Cutoff to Predict Waitlist Mortality in Liver Transplant Candidates.Kardashian A, Ge J, McCulloch CE, Kappus MR, Dunn MA, Duarte-Rojo A, Volk ML, Rahimi RS, Verna EC, Ganger DR, Ladner D, Dodge JL, Boyarsky B, McAdams-DeMarco M, Segev DL, Lai JC| | PubMed
- Outcomes of Liver Transplantation Among Older Recipients With Nonalcoholic Steatohepatitis in a Large Multicenter US Cohort: the Re-Evaluating Age Limits in Transplantation Consortium.Kwong AJ, Devuni D, Wang C, Boike J, Jo J, VanWagner L, Serper M, Jones L, Sharma R, Verna EC, Shor J, German MN, Hristov A, Lee A, Spengler E, Koteish AA, Sehmbey G, Seetharam A, John N, Patel Y, Kappus MR, Couri T, Paul S, Salgia RJ, Nhu Q, Frenette CT, Lai JC, Goel A, Re-Evaluating Age Limits in Transplantation (REALT) Consortium| | PubMed
- Unforeseen consequences of the COVID pandemic.Bucuvalas J, Lai JC| | PubMed
- Progression of Stage 2 and 3 Acute Kidney Injury in Patients With Decompensated Cirrhosis and Ascites.Wong F, Reddy KR, Tandon P, O'Leary JG, Garcia-Tsao G, Vargas HE, Lai JC, Biggins SW, Maliakkal B, Fallon M, Subramanian R, Thuluvath P, Kamath PS, Thacker L, Bajaj JS| | PubMed
- Neighborhood socioeconomic deprivation, racial segregation, and organ donation across 5 states.Wadhwani SI, Brokamp C, Rasnick E, Bucuvalas JC, Lai JC, Beck AF| | PubMed
- Association of motivations and barriers with participation and performance in a pedometer-based intervention.Sheshadri A, Kittiskulnam P, Delgado C, Sudore R, Lai JC, Johansen KL| | PubMed
- Psychological contributors to the frail phenotype: The association between resilience and frailty in patients with cirrhosis.Wong RJ, Mohamad Y, Srisengfa YT, Kent DS, Seetharaman S, Shah RJ, Lai JC| | PubMed
- Serum Levels of Metabolites Produced by Intestinal Microbes and Lipid Moieties Independently Associated With Acute-on-Chronic Liver Failure and Death in Patients With Cirrhosis.Bajaj JS, Reddy KR, O'Leary JG, Vargas HE, Lai JC, Kamath PS, Tandon P, Wong F, Subramanian RM, Thuluvath P, Fagan A, White MB, Gavis EA, Sehrawat T, de la Rosa Rodriguez R, Thacker LR, Sikaroodi M, Garcia-Tsao G, Gillevet PM| | PubMed
- Time for Action to Address the Persistent Sex-Based Disparity in Liver Transplant Access.Verna EC, Lai JC| | PubMed
- Frailty as an Immune-Mediated Condition That Leads to an Increased Risk of Acute Cellular Rejection in Liver Transplant Recipients.Fozouni L, Lai JC| | PubMed
- Liver Transplant Survivorship.Lai JC, Ufere NN, Bucuvalas JC| | PubMed
- Low Rates of Advance Care Planning (ACP) Discussions Despite Readiness to Engage in ACP Among Liver Transplant Candidates.Wang CW, Lebsack A, Sudore RL, Lai JC| | PubMed
- Multicenter Study of Age, Frailty, and Waitlist Mortality Among Liver Transplant Candidates.Haugen CE, McAdams-DeMarco M, Holscher CM, Ying H, Gurakar AO, Garonzik-Wang J, Cameron AM, Segev DL, Lai JC| | PubMed
- Aggressive utilization of liver allografts: Improved outcomes over time.Rana A, Price MB, Barrett SC, Lai J, Bakhtiyar SS, Kanwal F, Vierling J, Wu M, Galvan NT, Goss J| | PubMed
- Women who undergo liver transplant have longer length of stay post-transplant compared with men.Rubin JB, Cullaro G, Ge J, Lai JC| | PubMed
- Insurance Status But Not Race and Ethnicity Are Associated With Outcomes in a Large Hospitalized Cohort of Patients With Cirrhosis.Bajaj JS, O'Leary JG, Tandon P, Wong F, Kamath PS, Biggins SW, Garcia-Tsao G, Lai J, Fallon MB, Thuluvath PJ, Vargas HE, Maliakkal B, Subramanian RM, Thacker LR, Reddy KR| | PubMed
- Physical Function, Physical Activity, and Quality of Life After Liver Transplantation.Dunn MA, Rogal SS, Duarte-Rojo A, Lai JC| | PubMed
- Association of Karnofsky Performance Status with waitlist mortality among older and younger adults awaiting kidney transplantation.Sheshadri A, Cullaro G, Johansen KL, Lai JC| | PubMed
- Chronic Kidney Disease in Liver Transplant Candidates: A Rising Burden Impacting Post-Liver Transplant Outcomes.Cullaro G, Verna EC, Lee BP, Lai JC| | PubMed
- Changes in frailty are associated with waitlist mortality in patients with cirrhosis.Lai JC, Dodge JL, Kappus MR, Dunn MA, Volk ML, Duarte-Rojo A, Ganger DR, Rahimi RS, McCulloch CE, Haugen CE, McAdams-DeMarco M, Ladner DP, Segev DL, Verna EC, Multi-Center Functional Assessment in Liver Transplantation (FrAILT) Study| | PubMed
- Effect of a pedometer-based walking intervention on body composition in patients with ESRD: a randomized controlled trial.Sheshadri A, Kittiskulnam P, Lai JC, Johansen KL| | PubMed
- Underutilization of Hospice in Inpatients with Cirrhosis: The NACSELD Experience.O'Leary JG, Tandon P, Reddy KR, Biggins SW, Wong F, Kamath PS, Garcia-Tsao G, Maliakkal B, Lai J, Fallon M, Vargas HE, Thuluvath P, Subramanian R, Thacker LR, Bajaj JS| | PubMed
- Neighborhood socioeconomic deprivation is associated with worse patient and graft survival following pediatric liver transplantation.Wadhwani SI, Beck AF, Bucuvalas J, Gottlieb L, Kotagal U, Lai JC| | PubMed
- Frailty Is Associated With Increased Rates of Acute Cellular Rejection Within 3 Months After Liver Transplantation.Fozouni L, Mohamad Y, Lebsack A, Freise C, Stock P, Lai JC| | PubMed
- A Comprehensive Review of Outcome Predictors in Low MELD Patients.Mazumder NR, Atiemo K, Kappus M, Cullaro G, Harinstein ME, Ladner D, Verna E, Lai J, Levitsky J| | PubMed
- Response to "Reply to: 'The decreasing predictive power of MELD in an era of changing etiology of liver disease'".Godfrey EL, Malik TH, Lai JC, Mindikoglu AL, Galván NTN, Cotton RT, O'Mahony CA, Goss JA, Rana A| | PubMed
- Gender Differences Among Patients Hospitalized With Cirrhosis in the United States.Rubin JB, Sundaram V, Lai JC| | PubMed
- Split liver transplantation is utilized infrequently and concentrated at few transplant centers in the United States.Ge J, Perito ER, Bucuvalas J, Gilroy R, Hsu EK, Roberts JP, Lai JC| | PubMed
- Association Between Liver Transplant Wait-list Mortality and Frailty Based on Body Mass Index.Haugen CE, McAdams-DeMarco M, Verna EC, Rahimi RS, Kappus MR, Dunn MA, Volk ML, Gurakar A, Duarte-Rojo A, Ganger DR, O'Leary JG, Ladner D, Garonzik-Wang J, Segev DL, Lai JC| | PubMed
- Sex Differences in the Association Between Frailty and Sarcopenia in Patients With Cirrhosis.Fozouni L, Wang CW, Lai JC| | PubMed
- Differential Impact of Age Among Liver Transplant Candidates With and Without Hepatocellular Carcinoma.Cullaro G, Rubin JB, Mehta N, Lai JC| | PubMed
- Identifying a clinically relevant cutoff for height that is associated with a higher risk of waitlist mortality in liver transplant candidates.Ge J, Lai JC| | PubMed
- Sarcopenia Predicts Post-transplant Mortality in Acutely Ill Men Undergoing Urgent Evaluation and Liver Transplantation.Kuo SZ, Ahmad M, Dunn MA, Montano-Loza AJ, Carey EJ, Lin S, Moghe A, Chen HW, Ebadi M, Lai JC| | PubMed
- Frailty and the Burden of Concurrent and Incident Disability in Patients With Cirrhosis: A Prospective Cohort Study.Lai JC, Dodge JL, McCulloch CE, Covinsky KE, Singer JP| | PubMed
- Hospitalized Women With Cirrhosis Have More Nonhepatic Comorbidities and Associated Complications Than Men.Rubin JB, Srisengfa YT, Albhaisi S, Acharya C, Nangia G, Shaikh T, Thacker LR, Reddy KR, Tandon P, Bajaj JS, Lai JC| | PubMed
- Review article: impact of exercise on physical frailty in patients with chronic liver disease.Williams FR, Berzigotti A, Lord JM, Lai JC, Armstrong MJ| | PubMed
- The decreasing predictive power of MELD in an era of changing etiology of liver disease.Godfrey EL, Malik TH, Lai JC, Mindikoglu AL, Galván NTN, Cotton RT, O'Mahony CA, Goss JA, Rana A| | PubMed
- A North American Expert Opinion Statement on Sarcopenia in Liver Transplantation.Carey EJ, Lai JC, Sonnenday C, Tapper EB, Tandon P, Duarte-Rojo A, Dunn MA, Tsien C, Kallwitz ER, Ng V, Dasarathy S, Kappus M, Bashir MR, Montano-Loza AJ| | PubMed
- Barriers to ideal outcomes after pediatric liver transplantation.Ng VL, Mazariegos GV, Kelly B, Horslen S, McDiarmid SV, Magee JC, Loomes KM, Fischer RT, Sundaram SS, Lai JC, Te HS, Bucuvalas JC| | PubMed
- Nosocomial Infections Are Frequent and Negatively Impact Outcomes in Hospitalized Patients With Cirrhosis.Bajaj JS, O'Leary JG, Tandon P, Wong F, Garcia-Tsao G, Kamath PS, Biggins SW, Lai JC, Vargas HE, Maliakkal B, Fallon MB, Thuluvath PJ, Subramanian RM, Thacker LR, Reddy KR| | PubMed
- Impact of Muscle Gain after Transjugular Intrahepatic Portosystemic Shunt Creation on Patients Awaiting Liver Transplantation.Kohi MP, Lai JC| | PubMed
- Frailty in liver transplantation: An expert opinion statement from the American Society of Transplantation Liver and Intestinal Community of Practice.Lai JC, Sonnenday CJ, Tapper EB, Duarte-Rojo A, Dunn MA, Bernal W, Carey EJ, Dasarathy S, Kamath BM, Kappus MR, Montano-Loza AJ, Nagai S, Tandon P| | PubMed
- Changes in Simultaneous Liver-kidney Transplant Allocation Policy May Impact Postliver Transplant Outcomes.Cullaro G, Hirose R, Lai JC| | PubMed
- Split-Liver Allocation: An Underused Opportunity to Expand Access to Liver Transplantation.Ge J, Lai JC| | PubMed
- Targets to improve quality of care for patients with hepatic encephalopathy: data from a multi-centre cohort.Bajaj JS, O'Leary JG, Tandon P, Wong F, Kamath PS, Biggins SW, Garcia-Tsao G, Lai J, Fallon MB, Thuluvath PJ, Vargas HE, Maliakkal B, Subramanian RM, Thacker LR, Reddy KR| | PubMed
- The Range and Reproducibility of the Liver Frailty Index.Wang CW, Lebsack A, Chau S, Lai JC| | PubMed
- Impact of Chronic Kidney Disease on Outcomes in Cirrhosis.Wong F, Reddy KR, O'Leary JG, Tandon P, Biggins SW, Garcia-Tsao G, Maliakkal BJ, Lai JC, Fallon MB, Vargas HE, Subramanian R, Thuluvath PJ, Kamath PS, Thacker L, Bajaj JS| | PubMed
- Outcomes in Patients With Cirrhosis on Primary Compared to Secondary Prophylaxis for Spontaneous Bacterial Peritonitis.Bajaj JS, Tandon P, O'Leary JG, Wong F, Biggins SW, Garcia-Tsao G, Kamath PS, Maliakkal B, Fallon MB, Lai JC, Thuluvath PJ, Vargas HE, Subramanian RM, Thacker LR, Reddy KR| | PubMed
- Outcomes After Listing for Liver Transplant in Patients With Acute-on-Chronic Liver Failure: The Multicenter North American Consortium for the Study of End-Stage Liver Disease Experience.O'Leary JG, Bajaj JS, Tandon P, Biggins SW, Wong F, Kamath PS, Garcia-Tsao G, Maliakkal B, Lai J, Fallon M, Vargas HE, Thuluvath P, Subramanian R, Thacker LR, Reddy KR| | PubMed
- Women on the liver transplantation waitlist are at increased risk of hospitalization compared to men.Rubin JB, Sinclair M, Rahimi RS, Tapper EB, Lai JC| | PubMed
- Deceased Pediatric Donor Livers: How Current Policy Drives Allocation and Transplantation.Ge J, Hsu EK, Bucuvalas J, Lai JC| | PubMed
- Association Between Renal Function Pattern and Mortality in Patients With Cirrhosis.Cullaro G, Verna EC, Lai JC| | PubMed
- Frailty Associated With Waitlist Mortality Independent of Ascites and Hepatic Encephalopathy in a Multicenter Study.Lai JC, Rahimi RS, Verna EC, Kappus MR, Dunn MA, McAdams-DeMarco M, Haugen CE, Volk ML, Duarte-Rojo A, Ganger DR, O'Leary JG, Dodge JL, Ladner D, Segev DL| | PubMed
- Functional status at listing predicts waitlist and posttransplant mortality in pediatric liver transplant candidates.Perito ER, Bucuvalas J, Lai JC| | PubMed
- Report from the American Society of Transplantation on frailty in solid organ transplantation.Kobashigawa J, Dadhania D, Bhorade S, Adey D, Berger J, Bhat G, Budev M, Duarte-Rojo A, Dunn M, Hall S, Harhay MN, Johansen KL, Joseph S, Kennedy CC, Kransdorf E, Lentine KL, Lynch RJ, McAdams-DeMarco M, Nagai S, Olymbios M, Patel J, Pinney S, Schaenman J, Segev DL, Shah P, Singer LG, Singer JP, Sonnenday C, Tandon P, Tapper E, Tullius SG, Wilson M, Zamora M, Lai JC| | PubMed
- Sex hormone levels by presence and severity of cirrhosis in women with chronic hepatitis C virus infection.Sarkar M, Lai JC, Sawinski D, Zeigler TE, Cedars M, Forde KA| | PubMed
- How I Approach It: Improving Nutritional Status in Patients With Cirrhosis.Lai JC, Tandon P| | PubMed
- Poor performance of psoas muscle index for identification of patients with higher waitlist mortality risk in cirrhosis.Ebadi M, Wang CW, Lai JC, Dasarathy S, Kappus MR, Dunn MA, Carey EJ, Montano-Loza AJ, From the Fitness, Life Enhancement, and Exercise in Liver Transplantation (FLEXIT) Consortium| | PubMed
- Acute-on-Chronic Liver Failure: Getting Ready for Prime Time?Bajaj JS, Moreau R, Kamath PS, Vargas HE, Arroyo V, Reddy KR, Szabo G, Tandon P, Olson J, Karvellas C, Gustot T, Lai JC, Wong F| | PubMed
- Beta-blockers and physical frailty in patients with end-stage liver disease.Kuo SZ, Lizaola B, Hayssen H, Lai JC| | PubMed
- Patient and Caregiver Attitudes and Practices of Exercise in Candidates Listed for Liver Transplantation.Chascsa DM, Lai JC, Dunn MA, Montano-Loza AJ, Kappus MR, Dasarathy S, Carey EJ| | PubMed
- Determination of Free 25(OH)D Concentrations and Their Relationships to Total 25(OH)D in Multiple Clinical Populations.Schwartz JB, Gallagher JC, Jorde R, Berg V, Walsh J, Eastell R, Evans AL, Bowles S, Naylor KE, Jones KS, Schoenmakers I, Holick M, Orwoll E, Nielson C, Kaufmann M, Jones G, Bouillon R, Lai J, Verotta D, Bikle D| | PubMed
- Association Between Intestinal Microbiota Collected at Hospital Admission and Outcomes of Patients With Cirrhosis.Bajaj JS, Vargas HE, Reddy KR, Lai JC, O'Leary JG, Tandon P, Wong F, Mitrani R, White MB, Kelly M, Fagan A, Patil R, Sait S, Sikaroodi M, Thacker LR, Gillevet PM| | PubMed
- People who experience seclusion in adult mental health inpatient services: An examination of health of the nation outcome scales scores.Jury A, Lai J, Tuason C, Koning A, Smith M, Boyd L, Swanson C, Fergusson D, Gruar A| | PubMed
- "Normal" Creatinine Levels Predict Persistent Kidney Injury and Waitlist Mortality in Outpatients With Cirrhosis.Cullaro G, Park M, Lai JC| | PubMed
- The Impact of Albumin Use on Resolution of Hyponatremia in Hospitalized Patients With Cirrhosis.Bajaj JS, Tandon P, O'Leary JG, Biggins SW, Wong F, Kamath PS, Garcia-Tsao G, Maliakkal B, Lai JC, Fallon M, Thuluvath P, Vargas HE, Subramanian RM, Thacker LR, Reddy RK| | PubMed
- Receipt of a pediatric liver offer as the first offer reduces waitlist mortality for adult women.Ge J, Gilroy R, Lai JC| | PubMed
- Assessment of the spectrum of hepatic encephalopathy: A multicenter study.Reuter B, Walter K, Bissonnette J, Leise MD, Lai J, Tandon P, Kamath PS, Biggins SW, Rose CF, Wade JB, Bajaj JS| | PubMed
- Reply.Lai JC, Covinsky KE, Dodge JL, Boscardin WJ, Segev DL, Roberts JP, Feng S| | PubMed
- NACSELD acute-on-chronic liver failure (NACSELD-ACLF) score predicts 30-day survival in hospitalized patients with cirrhosis.O'Leary JG, Reddy KR, Garcia-Tsao G, Biggins SW, Wong F, Fallon MB, Subramanian RM, Kamath PS, Thuluvath P, Vargas HE, Maliakkal B, Tandon P, Lai J, Thacker LR, Bajaj JS| | PubMed
- Physical frailty after liver transplantation.Lai JC, Segev DL, McCulloch CE, Covinsky KE, Dodge JL, Feng S| | PubMed
- Association of Cardiac Abnormalities to the Frail Phenotype in Cirrhotic Patients on the Waitlist: From the Functional Assessment in Liver Transplantation Study.Puchades L, Chau S, Dodson JA, Mohamad Y, Mustain R, Lebsack A, Aguilera V, Prieto M, Lai JC| | PubMed
- Primary healthcare utilisation among adults with mood and anxiety disorders: an analysis of the New Zealand Health Survey.Lockett H, Lai J, Tuason C, Jury A, Fergusson D| | PubMed
- A2 liver transplantation across the ABO barrier: Increasing options in the donor pool?Ge J, Roberts JP, Lai JC| | PubMed
- Sex-based disparities in delisting for being "too sick" for liver transplantation.Cullaro G, Sarkar M, Lai JC| | PubMed
- Prediction of Fungal Infection Development and Their Impact on Survival Using the NACSELD Cohort.Bajaj JS, Reddy RK, Tandon P, Wong F, Kamath PS, Biggins SW, Garcia-Tsao G, Fallon M, Maliakkal B, Lai J, Vargas HE, Subramanian RM, Thuluvath P, Thacker LR, O'Leary JG| | PubMed
- The Liver Frailty Index Improves Mortality Prediction of the Subjective Clinician Assessment in Patients With Cirrhosis.Lai JC, Covinsky KE, McCulloch CE, Feng S| | PubMed
- Opioid and opioid substitution therapy in liver transplant candidates: A survey of center policies and practices.Fleming JN, Lai JC, Te HS, Said A, Spengler EK, Rogal SS| | PubMed
- Liver Transplantation in the Obese Cirrhotic Patient.Spengler EK, O'Leary JG, Te HS, Rogal S, Pillai AA, Al-Osaimi A, Desai A, Fleming JN, Ganger D, Seetharam A, Tsoulfas G, Montenovo M, Lai JC| | PubMed
- Transplant for the very sick: No limitations in donor quality?C Lai J| | PubMed
- Analysis of Liver Offers to Pediatric Candidates on the Transplant Wait List.Hsu EK, Shaffer ML, Gao L, Sonnenday C, Volk ML, Bucuvalas J, Lai JC| | PubMed
- Development of a novel frailty index to predict mortality in patients with end-stage liver disease.Lai JC, Covinsky KE, Dodge JL, Boscardin WJ, Segev DL, Roberts JP, Feng S| | PubMed
- Race/ethnicity is associated with ABO-nonidentical liver transplantation in the United States.Ge J, Roberts JP, Lai JC| | PubMed
- Reporting functional status in UNOS: The weakness of the Karnofsky Performance Status Scale.Wang CW, Lai JC| | PubMed
- A multicenter study to define sarcopenia in patients with end-stage liver disease.Carey EJ, Lai JC, Wang CW, Dasarathy S, Lobach I, Montano-Loza AJ, Dunn MA, Fitness, Life Enhancement, and Exercise in Liver Transplantation Consortium| | PubMed
- Cost-Effectiveness of Direct-Acting Antiviral Treatment in Hepatitis C-Infected Liver Transplant Candidates With Compensated Cirrhosis and Hepatocellular Carcinoma.Salazar J, Saxena V, Kahn JG, Roberts JP, Mehta N, Volk M, Lai JC| | PubMed
- Disability in patients with end-stage liver disease: Results from the functional assessment in liver transplantation study.Samoylova ML, Covinsky KE, Haftek M, Kuo S, Roberts JP, Lai JC| | PubMed
- Frailty is independently associated with increased hospitalisation days in patients on the liver transplant waitlist.Sinclair M, Poltavskiy E, Dodge JL, Lai JC| | PubMed
- A framework to determine when liver transplantation is futile.Lai JC| | PubMed
- Clinical Liver Disease| UCSF Research Profile
- Short Physical Performance Battery and all-cause mortality: systematic review and meta-analysis.Pavasini R, Guralnik J, Brown JC, di Bari M, Cesari M, Landi F, Vaes B, Legrand D, Verghese J, Wang C, Stenholm S, Ferrucci L, Lai JC, Bartes AA, Espaulella J, Ferrer M, Lim JY, Ensrud KE, Cawthon P, Turusheva A, Frolova E, Rolland Y, Lauwers V, Corsonello A, Kirk GD, Ferrari R, Volpato S, Campo G| | PubMed
- Factors Associated with Medication Non-adherence in Patients with End-Stage Liver Disease.Kuo SZ, Haftek M, Lai JC| | PubMed
- Editorial: Advancing Adoption of Frailty to Improve the Care of Patients with Cirrhosis: Time for a Consensus on a Frailty Index.Lai JC| | PubMed
- Performance-Based Measures Associate With Frailty in Patients With End-Stage Liver Disease.Lai JC, Volk ML, Strasburg D, Alexander N| | PubMed
- Acute Liver Failure Secondary to Hemophagocytic Lymphohistiocytosis during Pregnancy.Giard JM, Decker KA, Lai JC, Gill RM, Logan AC, Fix OK| | PubMed
- Hepatic Encephalopathy Is Associated With Mortality in Patients With Cirrhosis Independent of Other Extrahepatic Organ Failures.Bajaj JS, O'Leary JG, Tandon P, Wong F, Garcia-Tsao G, Kamath PS, Maliakkal B, Biggins SW, Thuluvath PJ, Fallon MB, Subramanian RM, Vargas HE, Lai J, Thacker LR, Reddy KR| | PubMed
- Underutilization of palliative care services in the liver transplant population.Kathpalia P, Smith A, Lai JC| | PubMed
- A Comparison of Muscle Function, Mass, and Quality in Liver Transplant Candidates: Results From the Functional Assessment in Liver Transplantation Study.Wang CW, Feng S, Covinsky KE, Hayssen H, Zhou LQ, Yeh BM, Lai JC| | PubMed
- ABO-Nonidentical Liver Transplantation in the United States.Lai JC, Roberts JP| | PubMed
- Defining the threshold for too sick for transplant.Lai JC| | PubMed
- Response to clinical assessments of health status as a potential marker to identify patients who are too sick to undergo transplantation.Lai JC, Covinsky KE, Hayssen H, Lizaola B, Dodge J, Roberts JP, Terrault NA, Feng S| | PubMed
- Functional decline in patients with cirrhosis awaiting liver transplantation: Results from the functional assessment in liver transplantation (FrAILT) study.Lai JC, Dodge JL, Sen S, Covinsky K, Feng S| | PubMed
- Functional impairment in older liver transplantation candidates: From the functional assessment in liver transplantation study.Wang CW, Covinsky KE, Feng S, Hayssen H, Segev DL, Lai JC| | PubMed
- Outcomes for liver transplant candidates listed with low model for end-stage liver disease score.Kwong AJ, Lai JC, Dodge JL, Roberts JP| | PubMed
- Kidney Failure and Liver Allocation: Current Practices and Potential Improvements.Saxena V, Lai JC| | PubMed
- Decision support for organ offers in liver transplantation.Volk ML, Goodrich N, Lai JC, Sonnenday C, Shedden K| | PubMed
- Hepatitis C genotype influences post-liver transplant outcomes.Campos-Varela I, Lai JC, Verna EC, O'Leary JG, Todd Stravitz R, Forman LM, Trotter JF, Brown RS, Terrault NA, Consortium to Study Health Outcomes in HCV Liver Transplant Recipients (CRUSH-C)| | PubMed
- Total 25(OH) vitamin D, free 25(OH) vitamin D and markers of bone turnover in cirrhotics with and without synthetic dysfunction.Lai JC, Bikle DD, Lizaola B, Hayssen H, Terrault NA, Schwartz JB| | PubMed
- Clinician assessments of health status predict mortality in patients with end-stage liver disease awaiting liver transplantation.Lai JC, Covinsky KE, Hayssen H, Lizaola B, Dodge JL, Roberts JP, Terrault NA, Feng S| | PubMed
- Bone Mineral Density, Bone Turnover, and Systemic Inflammation in Non-cirrhotics with Chronic Hepatitis C.Lai JC, Shoback DM, Zipperstein J, Lizaola B, Tseng S, Terrault NA| | PubMed
- Role of delta-aminolevulinic acid in the symptoms of acute porphyria.Bissell DM, Lai JC, Meister RK, Blanc PD| | PubMed
- Combined effects of recipient age and model for end-stage liver disease score on liver transplantation outcomes.Sharpton SR, Feng S, Hameed B, Yao F, Lai JC| | PubMed
- The octogenarian donor: can the liver be "younger than stated age"?Lai JC, Covinsky K, Feng S| | PubMed
- Expanded criteria donors.Feng S, Lai JC| | PubMed
- Frailty predicts waitlist mortality in liver transplant candidates.Lai JC, Feng S, Terrault NA, Lizaola B, Hayssen H, Covinsky K| | PubMed
- A comparison of measured and calculated free 25(OH) vitamin D levels in clinical populations.Schwartz JB, Lai J, Lizaola B, Kane L, Markova S, Weyland P, Terrault NA, Stotland N, Bikle D| | PubMed
- Variability in free 25(OH) vitamin D levels in clinical populations.Schwartz JB, Lai J, Lizaola B, Kane L, Weyland P, Terrault NA, Stotland N, Bikle D| | PubMed
- Reducing infection transmission in solid organ transplantation through donor nucleic acid testing: a cost-effectiveness analysis.Lai JC, Kahn JG, Tavakol M, Peters MG, Roberts JP| | PubMed
- Offer patterns of nationally placed livers by donation service area.Lai JC, Feng S, Vittinghoff E, Roberts JP| | PubMed
- Center competition and outcomes following liver transplantation.Halldorson JB, Paarsch HJ, Dodge JL, Segre AM, Lai J, Roberts JP| | PubMed
- Sudden onset vision loss in an 8-year-old female with McCune-Albright syndrome.Kim D, Wysong A, Lai J, Alcorn DM, Benjamin LT| | PubMed
- An examination of liver offers to candidates on the liver transplant wait-list.Lai JC, Feng S, Roberts JP| | PubMed
- Recipient-donor race mismatch for African American liver transplant patients with chronic hepatitis C.Saxena V, Lai JC, O'Leary JG, Verna EC, Brown RS, Stravitz RT, Trotter JF, Krishnan K, Terrault NA, Consortium to Study Health Outcomes in HCV Liver Transplant Recipients| | PubMed
- Risk of advanced fibrosis with grafts from hepatitis C antibody-positive donors: a multicenter cohort study.Lai JC, O'Leary JG, Trotter JF, Verna EC, Brown RS, Stravitz RT, Duman JD, Forman LM, Terrault NA, Consortium to Study Health Outcomes in HCV Liver Transplant Recipients (CRUSH-C)| | PubMed
- Effects of ethnicity and socioeconomic status on survival and severity of fibrosis in liver transplant recipients with hepatitis C virus.Verna EC, Valadao R, Farrand E, Pichardo EM, Lai JC, Terrault NA, Brown RS| | PubMed
- Patient, center and geographic characteristics of nationally placed livers.Lai JC, Roberts JP, Vittinghoff E, Terrault NA, Feng S| | PubMed
- Hepatic steatosis at 1 year is an additional predictor of subsequent fibrosis severity in liver transplant recipients with recurrent hepatitis C virus.Brandman D, Pingitore A, Lai JC, Roberts JP, Ferrell L, Bass NM, Terrault NA| | PubMed
- Hepatitis C virus-infected women have a higher risk of advanced fibrosis and graft loss after liver transplantation than men.Lai JC, Verna EC, Brown RS, O'Leary JG, Trotter JF, Forman LM, Duman JD, Foster RG, Stravitz RT, Terrault NA, Consortium to Study Health Outcomes in HCV Liver Transplant Recipients (CRUSH-C)| | PubMed
- Gender differences in liver donor quality are predictive of graft loss.Lai JC, Feng S, Roberts JP, Terrault NA| | PubMed
- Height contributes to the gender difference in wait-list mortality under the MELD-based liver allocation system.Lai JC, Terrault NA, Vittinghoff E, Biggins SW| | PubMed
- Lessons from HIV therapy applied to viral hepatitis therapy: summary of a workshop.Monto A, Schooley RT, Lai JC, Sulkowski MS, Chung RT, Pawlotsky JM, McHutchison JG, Jacobson IM| | PubMed
- A novel housestaff educational model for quaternary-care patients at an academic health center.Lai JC, Montero A, Lebwohl B, Brown RS| | PubMed
- Resource utilization of living donor versus deceased donor liver transplantation is similar at an experienced transplant center.Lai JC, Pichardo EM, Emond JC, Brown RS| | PubMed